A group of teens in the pediatric ward of Los Angeles' Ocean Park Hospital find comfort in one another. Mexican-born Jordi, 16, crossed the border for treatment. His roommate, Leo, at the hospital for over a year, is starting to lose his way. Cystic fibrosis prompts Leo's best friend, Dash, to live each day as though it's his last. Emma, Leo's off-and-on girlfriend, has an eating disorder. Kara is a cheerleader with a heart problem, and her roommate, Charlie, is 12 and in a coma. Dr. Jack McAndrew and Nurses Jackson and Dobler make up their medical team.