Osmosis Jones

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Osmosis Jones

PG

Released Aug 10, 2001

1h 38m

Kids & Family

Comedy

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Tomatometer

Popcornmeter

55%

Tomatometer

112 Reviews

42%

Popcornmeter

50,000+ Ratings

A cutting-edge, live action/animated action adventure comedy about one white blood cell's (Chris Rock) race against the biological clock to hunt down and destroy a lethal new virus (Laurence Fishburne). Bill Murray stars as Frank, in whose body the action unfolds.

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Critics Consensus

The animated portion of Osmosis is zippy and fun, but the live-action portion is lethargic.

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Nell Minow

Common Sense Media

Mostly animated PG film has gross-out humor, violence.

Rated: 3/5

Dec 26, 2010

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Time Out

The plot's so much old rote, and the characters have all the personality of protoplasm; but the anthropomorphising of this microcosmic metropolis is wonderfully imaginative, and the dialogue decidedly spiffy.

Jan 26, 2006

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Kimberley Jones

Austin Chronicle

The ideas are there, hints of genius, but no one ignites them.

Rated: 2/5

Mar 10, 2003

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Dan DiNicola

The Daily Gazette (Schenectady, NY)

It's imaginative, ingenious and dramatically flat. Still, it may satisfy his who will learn a lot about the nasty effects of junk food on the human body.

Rated: C+

Apr 30, 2024

Full Review

Korey Coleman

Double Toasted

It sometimes lets its imagination cut loose in a fun way. But a lot of the movie is just puns, body humor, jokes...but some of the parts, they do very well with it...

May 11, 2020

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Erik Anderson

AwardsWatch

...one of the smartest, funniest and most eye-popping films of the year.

Rated: 3.5/4

Apr 7, 2020

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CHARLOTTE B

i cant find a movie mother suckers

Rated 1 out of 5 stars

06/12/25

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Hex x

Enjoyable movie, especially for kids.

Rated 3.5 out of 5 stars

04/30/25

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shrek d

i'll be puffin like diddy

Rated 0.5 out of 5 stars

03/31/25

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Amir S

A reasonable but interesting film, in a strange way it reminds me of the film "Saw 9".

Rated 3 out of 5 stars

03/26/25

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Audience Member

A solidly animated film with gross-out live action humor that preaches cleanliness. I think that was the message. But it has a soft spot in my heart for a embodying a time when WB was still adventurous and their cartoon universe was thriving with talent and potential. Today WBD loathes the toons. RIP Coyote v Acme.

Rated 4 out of 5 stars

03/08/25

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TROY S

Just simple content like that makes "Osmosis Jones" worth a watch. Even adults will enjoy the live action humor, as well as the film's zest, energy, and irony.

Rated 5 out of 5 stars

02/10/25

Full Review

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Peter Farrelly

Director

Robert Farrelly

Director

Bill Murray

Frank

Molly Shannon

Mrs. Boyd

Chris Elliott

Bob

Elena Franklin

Shane Detomello

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Synopsis

A cutting-edge, live action/animated action adventure comedy about one white blood cell's (Chris Rock) race against the biological clock to hunt down and destroy a lethal new virus (Laurence Fishburne). Bill Murray stars as Frank, in whose body the action unfolds.

Director: Peter Farrelly, Robert Farrelly
Producer: Peter Farrelly, Robert Farrelly, Bradley Thomas, Zak Penn, Dennis Edwards
Screenwriter: Marc Hyman
Distributor: Warner Bros. Pictures
Production Co: Warner Brothers, Conundrum Entertainment
Rating: PG (Bodily Humor)
Genre: Kids & Family, Comedy
Original Language: English
Release Date (Theaters): Aug 10, 2001, Wide
Release Date (Streaming): Dec 3, 2007
Box Office (Gross USA): $13.6M
Runtime: 1h 38m
Sound Mix: Dolby SR, DTS, Dolby Stereo, Surround, SDDS, Dolby A, Dolby Digital
Aspect Ratio: Scope (2.35:1)

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