Exploring the fun and harrowing world of high school for the offspring of zombies, ghouls, and other undead creatures. Following the day-to-day antics of Frankie Stein, who, along with friends Draculaura, Clawdeen, and Lagoona Blue, enjoys parties, gossip, and of course, crushes on "mansters" like Deuce Gorgon and pop singers like Justin Biter and the Jaundice Brothers. Also adding to the fray is frenemy Cleo De Nile and her sidekick, Ghoulia Yelps. There's never a dull moment, especially when they are under pressure to fit in, look good, be popular, and find a date, but it's everything that high school should be.