William Masters and Virginia Johnson are known as pioneers of the science of human sexuality. Their research shoots them to fame on a trajectory that takes them from humble beginnings in the Midwest to the cover of Time magazine. Masters is a brilliant scientist who is out of touch with his own feelings. Johnson is a divorced mother who is ahead of her time on many fronts, including her determination to have a meaningful career. The pair's relationship isn't just professional, as it evolves into a three-way "marriage" with Masters' wife, Libby. "Masters of Sex" is based on Thomas Maier's book of the same name, which profiled the pair.
- Starring: Michael Sheen, Lizzy Caplan, Caitlin FitzGerald, Annaleigh Ashford, Teddy Sears
- TV Network: Showtime
- Premiere Date: Sep 29, 2013
- Genre: Romance
- Executive producers: Michelle Ashford, Sarah Timberman, Carl Beverly, Judith Verno, Amy Lippman