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Season 2 – St. Denis Medical

Play trailer Poster for Season 2 – St. Denis Medical Next Ep Dec 1 Comedy Play Trailer Watchlist
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Devoted nurse Alex has just been promoted to Supervising Nurse in the emergency department at St. Denis Medical Center in Oregon. She works alongside an eclectic team of underfunded yet dedicated doctors, nurses and hospital staff, including her boss, Joyce, who wants nothing more than to turn the hospital into an international medical destination, and Dr. Ron, who's done it all, seen it all and is pretty much over it all. They're all doing their best not to lose their patience in a hospital overrun with patients -- while caring for everyone who comes in the door, including each other.
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St. Denis Medical — Season 2

Critics Reviews

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Sofía Aguilar LatinaMedia.Co “St. Denis Medical” season 2 takes what we’ve seen before in its own direction, giving new laughs and insights on workplace “families.” Nov 11, 2025 Full Review Joel Keller Decider St. Denis Medical is entering its second season as a workplace comedy who knows who its characters are and how to craft stories and humor around that, which is always what shows like this should aspire to do. Nov 7, 2025 Full Review Read all reviews

Audience Reviews

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Tom G Cannot believe they renewed this turkey! Not smart, usually not funny. Bad acting, worse writing, horrible character design. Shallow plots. Hate the characters. The strong, but inept administrator, the conceited surgeon, the grouch ER doc, the insecure head nurse, plus the one dimensional nursing staff are difficult to empathize with. Rated 1 out of 5 stars 11/19/25 Full Review micah C. St. Denis season two brings us back into this world full of joy. We get to see our favorite characters come back better than ever even when some jokes fall flat. This show has the same heart and humor superstore had and I can’t wait to continue season 2. Rated 4 out of 5 stars 11/08/25 Full Review Read all reviews
St. Denis Medical — Season 2

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Cast & Crew

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Wendi McLendon-Covey

Joyce

David Alan Grier

Ron

Allison Tolman

Alex

Josh Lawson

Bruce

Kahyun Kim

Serena

Mekki Leeper

Matt

Episodes

Episode 1 Aired Nov 3, 2025 Aloha, Everyone Alex tries to hold on to her peaceful vacation vibes; Joyce faces a design crisis in the birthing center; Matt and Serena reassess their working relationship. Details Episode 2 Aired Nov 3, 2025 Mama Bear Activated After Bruce is attacked at the hospital, Matt helps him deal with the aftermath; Alex motivates Joyce to amp up security, while Ron and Serena debate who is more qualified to defend themselves. Details Episode 3 Aired Nov 10, 2025 Get Me in the Pod, Brother Alex and Ron spar over the wisdom of open communication; Joyce brings in a body scanner that proves overly distracting. Details Episode 4 Aired Nov 17, 2025 Two Docs, One Conf Ron and Bruce butt heads at a medical conference; Joyce tries to show her nurses some love for Nurse Appreciation Week. Details Episode 5 Aired Nov 24, 2025 A Strong Cup of Coffee Alex is eager to impress her old charge nurse, Pam, who comes back to St. Denis; Serena and Matt try to solve a patient's mystery illness. Details Episode 6 Airs Dec 1 I Left a Woman on the Table Matt struggles to deal with a patient from his past; Bruce tries to rekindle romance with a former flame; Joyce treats patients to cover a nursing shortage. Details Episode 7 Airs Dec 8 No Wonder His Kidney Wants Out Ron and Alex react very differently to a seemingly selfless patient; Joyce runs into an old flame; Matt helps Bruce find a new best friend. Details

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St. Denis Medical — Season 2

St. Denis Medical St. Denis Medical St. Denis Medical View more photos

Season Info

Director
Matt Sohn, Tristram Shapeero, Heather Jack, Randall Winston, Bill Benz, Richie Keen, Yana Gorskaya
Executive Producer
Justin Spitzer, Eric Ledgin, Simon Heuer
Screenwriter
Eric Ledgin, Jeremy Bronson, Owen Ellickson, Bridget Kyle, Justin Shanes, Hunter Toro, Kyle Mack, Vicky Luu
Network
NBC
Rating
TV-14 (L|D)
Genre
Comedy
Original Language
English
Release Date
Nov 3, 2025
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