Inspired by comic Chelsea Handler's book "Are You There Vodka? It's Me, Chelsea," this sitcom features Chelsea (Laura Prepon), a strong-willed bartender in her twenties who takes life by the horns and doesn't apologize for it. She is joined by co-workers and friends who realize she is a force to be reckoned with. Chelsea shares her apartment with shy and sheltered Dee Dee. Handler herself has a recurring role as Chelsea's sister, Sloan, a new mom who shares little in common with her carefree sister.
- Starring: Laura Prepon, Mark Povinelli, Chelsea Handler, Lauren Lapkus, Ali Wong
- TV Network: NBC
- Premiere Date: Jan 11, 2012
- Genre: Comedy
- Executive producers: Dottie Zicklin, Julie Larson, Chelsea Handler, Tom Werner, Mike Clements, Tom Brunelle